PRODUCTS SOLD ON PEPTIDESLABUAE.COM ARE FOR RESEARCH PURPOSES ONLY AND ARE NOT FOR HUMAN OR VETERINARY USE.
PRODUCTS SOLD ON PEPTIDESLABUAE.COM ARE FOR RESEARCH PURPOSES ONLY AND ARE NOT FOR HUMAN OR VETERINARY USE.
£69.00
P21 is a widely researched peptide known for its role in cognitive function and neuroprotective studies. Each batch is independently verified at ≥99% purity and comes with a full Certificate of Analysis (COA) and HPLC testing documentation — giving UAE research teams the confidence they need when sourcing peptides for serious work.
For research use only. Not intended for human or veterinary use.
P21 is a synthetic nootropic peptide studied in neuroscience research for its role in BDNF (Brain-Derived Neurotrophic Factor) pathway modulation, neuroplasticity, and cognitive function models — making it one of the more targeted research compounds available for laboratories investigating neural growth signalling and brain biology. Researchers and institutions across the UAE, Dubai, Abu Dhabi and the wider GCC can source verified, research-grade P21 with fast international dispatch and full batch documentation included.
✅ ≥99% Purity — HPLC Verified ✅ Batch-Specific Certificate of Analysis (CoA) Included ✅ Lyophilised Powder | GMP Manufactured ✅ Fast International Dispatch to UAE & GCC
P21 is a synthetic peptide derived from CNTF (Ciliary Neurotrophic Factor) — a naturally occurring protein involved in neuronal survival and development. What makes P21 particularly interesting as a research tool is its design: it was developed to interact with BDNF signalling pathways while avoiding some of the receptor binding complexities associated with full CNTF. Specifically, P21 has been studied for its ability to increase BDNF levels and inhibit SOCS2 (Suppressor of Cytokine Signalling 2) — a protein that can limit neurotrophin signalling when overexpressed.
Its focused mechanism, combined with growing research interest in BDNF’s role in neuroplasticity, memory, and neural resilience, has made P21 a relevant and increasingly sought-after compound for neuroscience laboratories. Research institutions across the UAE and GCC studying cognitive biology and neurological function have shown growing interest in P21 as part of broader neurotrophic research programmes.
In controlled laboratory settings, P21 has been investigated across several interconnected areas of neuroscience research:
BDNF Pathway Modulation: P21’s primary research focus is its influence on BDNF — one of the most important neurotrophins in the brain, involved in neuronal survival, synaptic plasticity, and the formation of new neural connections. Studies have examined how P21 affects BDNF expression and downstream signalling in neural cell models.
SOCS2 Inhibition: Research has explored P21’s role in inhibiting SOCS2, a regulatory protein that suppresses cytokine and neurotrophin signalling. By reducing SOCS2 activity, P21 is studied as a tool for examining what happens when neurotrophin signalling is disinhibited in neural tissue models.
Neuroplasticity Research: Studies have used P21 in models examining synaptic plasticity — the ability of neural connections to strengthen or weaken over time — which is fundamental to how the brain adapts, learns, and processes information at the cellular level.
Cognitive Function Models: P21 has been incorporated into pre-clinical research examining learning, memory consolidation, and cognitive performance parameters in animal models, making it relevant to neuroscience teams studying the cellular basis of cognition.
Neurogenesis Studies: Research has examined P21’s effects on neural progenitor cell behaviour and new neuron formation in hippocampal models — an area closely linked to memory and spatial navigation research.
Neuroprotection Research: Studies have explored P21 in models examining how neural cells respond to stress and injury, looking at whether BDNF pathway enhancement influences neuronal survival under challenging conditions.
All applications listed are research-based only. P21 is not approved for human therapeutic use.
P21 has a focused but growing pre-clinical research profile centred on neurotrophic and cognitive biology:
Research examining P21’s effects on BDNF expression has documented increases in BDNF levels in neural tissue models following P21 administration, supporting its utility as a tool for studying BDNF-dependent processes in controlled experimental settings. Pre-clinical cognitive studies have reported changes in learning and memory parameters in animal models treated with P21, with research examining performance across spatial memory and novel object recognition tasks. Studies investigating P21’s SOCS2 inhibitory activity have provided insights into how suppressing this regulatory protein affects downstream neurotrophin signalling cascades, contributing to a broader understanding of how BDNF pathway regulation influences neural function. Neurogenesis research has examined P21’s influence on hippocampal cell proliferation models, reflecting interest in how BDNF pathway enhancement affects new neuron formation in brain regions associated with memory. Its relatively simple peptide structure combined with its targeted mechanism has made P21 a practical research tool for neuroscience teams compared to working with full CNTF protein, which carries greater complexity in experimental settings.
| Parameter | Specification |
|---|---|
| Peptide Origin | Derived from CNTF sequence |
| Primary Research Target | BDNF pathway / SOCS2 inhibition |
| Purity | ≥99% (HPLC Verified) |
| Form | White Lyophilised Powder |
| Solubility | Sterile water, bacteriostatic water |
| Storage (powder) | -20°C, protect from light |
| Storage (reconstituted) | 2–8°C, use within 2–4 weeks |
Every order of P21 dispatched to the UAE and GCC includes:
Can I buy P21 peptide in the UAE?
Yes. We supply research-grade P21 with international dispatch to the UAE, Dubai, Abu Dhabi, Sharjah and across the GCC. All orders include full batch documentation and are packaged to maintain peptide integrity throughout transit.
What is the relationship between P21 and BDNF?
P21 is studied for its ability to upregulate BDNF — Brain-Derived Neurotrophic Factor — a key protein in neuronal survival, synaptic plasticity, and neural development. Research uses P21 as a tool to examine what happens to neural function and structure when BDNF signalling is enhanced, making it relevant to studies across neuroplasticity, memory, and neuroprotection research.
What is SOCS2 and why is its inhibition relevant to neuroscience research? SOCS2 (Suppressor of Cytokine Signalling 2) is a regulatory protein that can dampen neurotrophin and cytokine signalling when overexpressed. Research into P21’s SOCS2 inhibitory activity examines whether reducing this suppression allows neurotrophic signalling — particularly BDNF — to operate with greater activity, and what downstream effects this produces in neural cell and animal models.
How is P21 different from working with full CNTF in research?
Full CNTF (Ciliary Neurotrophic Factor) is a large protein with complex receptor interactions across multiple signalling pathways. P21 is a smaller synthetic peptide derived from CNTF’s sequence, designed to engage more selectively with specific aspects of the neurotrophic signalling system. This makes P21 a more practical and targeted research tool for laboratories studying BDNF pathway modulation specifically.
What purity is required for P21 neuroscience research?
A minimum of ≥98% is considered research grade, though ≥99% is strongly preferred for sensitive neurological assays, BDNF measurement studies, and cell culture experiments where compound purity directly affects result accuracy. All our P21 is independently verified to ≥99%.
How is P21 reconstituted for laboratory use?
Allow the vial to reach room temperature before opening. Add sterile or bacteriostatic water slowly down the vial wall and swirl gently without shaking. Aliquot immediately if longer-term storage at -80°C is required to avoid freeze-thaw degradation and maintain peptide integrity.
How quickly is P21 delivered to UAE?
Orders are dispatched promptly via tracked international courier. Delivery to the UAE typically takes 3–5 working days, with packaging designed to maintain peptide stability throughout transit.
Research Disclaimer: P21 is supplied exclusively for legitimate scientific research purposes conducted within licensed laboratory environments. This product is not intended for human consumption, self-administration, or any therapeutic application. It must be handled by qualified researchers in compliance with applicable UAE regulations and institutional ethics guidelines. Handling should only be performed by qualified laboratory professionals in controlled research settings. By purchasing, you confirm that this compound will be used solely for approved in-vitro or pre-clinical research purposes.
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